I don’t believe it is smart to lease the immune systems of the masses out to entities who have track records of harming humans.
1. You aren't necessarily protected
Meaning you are still prone to catching infectious disease vaccinated or not.
As this CDC article highlights:
In recent years, two major types of outbreaks have occurred in the United States: those among unvaccinated preschool-aged children, including those younger than the recommended age for vaccination (i.e., less than 15 months), and those among vaccinated school-aged children.
2. You will be capable of spreading and shedding vaccine derived disease
Whether it is disease from the live virus or some random strain mutation as a direct result of receiving the vaccination, history has shown that, time and time again, Vaccinated humans spread infectious disease.
Scientific evidence demonstrates that individuals vaccinated with live virus vaccines such as MMR (measles, mumps and rubella), rotavirus, chicken pox, shingles and influenza can shed the virus for many weeks or months afterwards and infect the vaccinated and unvaccinated alike.
3. Compromising your body's natural immune system response
Not only are you avoiding your bodies natural immune response by having the inoculation injected directly into the body as opposed to getting it through the natural avenues, but you are compromising it by distracting it in a way its not used to which allows other infections to take over.
Vaccinating is not the only way to obtain a portion of the population with a high threshold of immunity. In fact the immunity received by humans when allowing it to be generated naturally is actually life long and is more reliable than the generic version offered up by vaccine companies. Vaccination replaces wild exposure with artificial exposure, and they are not equal.
4. You have all of the risk and no person or entity can ever be held accountable
Since the 80's the vaccine companies have laid the foundation for blanket immunity and have been patching in the holes ever since. With no incentive to make vaccines safe and a large and lucrative market guaranteed by the CDC’s vaccine schedule—on children and now preteens, adults, and elderly alike—vaccine manufacturers appear to have it made.
5. Weakening and altering the genome over generations
Perhaps the scariest and most dangerous to humans as a whole. Weakening and altering the genome of multiple generations by making vaccinations mandatory.